About
Dr Jasmin Straube is a Cancer Council Queensland Next Generation Cancer research fellow (CCQ). She received her PhD in developing statistical methods and tools for the analysis and integration of ‘omics data from the University of Queensland in 2017.
Following this she joined Prof. Steven Lane’s group at QIMR Berghofer where she investigates how mutations in haematopoietic stem cells lead to the development of myeloid blood cancers and therapy resistance.
She led a study assessing the genetic risk of responding to chemotherapy in acute myeloid leukaemia (AML). This data helps clinicians to decide how to treat AML patients. She also was a lead author on a study that identified AML oncogenes vary in their potential to interact with the immune system, which will inform the implementation of immunotherapies in the clinic.
Her current research focuses on developing sequencing and bioinformatics methods to study how complex genetic heterogeneity in myeloid blood cancer patient haematopoietic stem cells contribute to therapy resistance and disease progression. Additionally, she is working to identify novel strategies that can effectively eliminate myeloid cancer-driving stem cells, ultimately improving patient treatment and outcomes.
Area of Interest
Blood cancer
Genetic heterogeneity in myeloid blood cancer
Treatment resistance
Sequencing and bioinformatics