The impact of our research
QIMR Berghofer is dedicated to advancing Alzheimer's disease research in order to better understand its underlying causes, improve diagnosis, and identify new treatment targets.
Currently there is no cure for Alzheimer’s disease, and no treatment can stop the progression completely, although some drugs can slow the decline in thinking ability and memory loss.
In a major advance for the treatment of Alzheimer’s disease, our researchers have overcome a significant obstacle by successfully delivering drugs through patient cell models of the human blood-brain barrier.
Our scientists have found several drugs that target the activity of genes linked to Alzheimer’s disease.
A new study has identified a list of existing drugs that could potentially be repurposed to alleviate symptoms of Alzheimer’s disease.
About Alzheimer's disease research
Alzheimer's disease is a progressive and irreversible brain disorder that affects memory, thinking abilities, and behavior. It is the most common cause of dementia, a term used to describe a group of symptoms related to cognitive decline and memory loss.
Alzheimer's disease research is vital to better understanding the drivers of Alzheimer’s, and the mechanisms involved in affecting the brain are our best hope of developing new, life-changing treatments.
One of the great challenges of Alzheimer’s disease is diagnosis. While there is no single test to diagnose Alzheimer’s, diagnosis can made after careful clinical consultation.
Early diagnosis is vital. Although we can’t yet cure Alzheimer’s, we can slow its progression. This improves quality of life for people with the condition, potentially for decades.
Health and lifestyle factors contribute to the development of Alzheimer’s disease, but we don't know the exact reason why some people develop Alzheimer’s disease and others do not.
Anyone can get Alzheimer’s disease, however it is most common in people over 65 and increases with age.
Symptoms of Alzheimer’s change as the condition progresses and can include:
- Memory loss;
- Vagueness in conversation;
- Changes in personality or mood;
- Repeatedly saying the same thing, or telling the same stories;
- Language or comprehension difficulties;
- Disorientation.
There is currently no cure for Alzheimer’s disease, and no treatment can stop the progression of the disease. Current medications aim to slow the decline in cognitive ability and memory loss, other drugs can be used to manage symptoms.