Research Focus
The Hepatic Fibrosis Laboratory investigates the cellular and molecular mechanisms of scar tissue formation in the liver. In adults, this leads to fibrosis and cirrhosis and diseases such as haemochromatosis. In children, this leads to diseases such as cystic fibrosis and biliary atresia. If left untreated chronic liver disease can lead to liver cancer.
Gallery
Research Projects
Current Research Projects
Development of microRNAs as anti-fibrotic agents to treat organ fibrosis..
Characterisation of anti-inflammatory molecules and signalling pathways to treat liver inflammation, fibrogenesis and cirrhosis..
Non-invasive biomarkers of liver disease and fibrosis in haemochromatosis..
Research Team
Dr Michael Pearen
Dr Glicia Maria De Almeida
Dr Silvia Luiza Saggiomo
Diem Hoang-Le
Funding
- National Health and Medical Research Council.
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
Further Information
Internal Collaborations
External Collaborations
- Associate Professor Peter Lewindon, Queensland Children’s Hospital.
- Professor Darrell Crawford, Greenslopes Hospital and University of Queensland.
- Professor John Olynyk, Edith Cowan University, Western Australia.
- A/Professor Janina Tirnitz-Parker, Curtain University, Western Australia.
- Professor Gary Jeffrey, University of Western Australia and Sir Charles Gairdner Hospital.
- Dr Martin Delatycki, Murdoch Children’s Research Institute.
- Dr Richard Skoien, Royal Brisbane and Women’s Hospital, Brisbane.
- Professor Nathan Subramaniam, Queensland University of Technology, Brisbane.
- A/Professor Sumaira Husnain, Translational Research Institute, Brisbane.
- Professor Paulo Arosio, University of Brescia, Italy.
- Professor Christine McLaren & Professor Gordon McLaren, University of California (Irvine).
- Dr Daniel Leung, Baylor College of Medicine, Houston, Texas
- Professor Carla Colombo, University of Milan, Italy.
- Professor Edouard Bardou-Jacquet, University of Rennes, France.
- A/Professor Dirk Schmidt-Arras, University of Kiel, Germany.
- Dr Amanda Abou-Fadel, Children’s Hospital at Montefiore, The Bronx, New York.